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Article

HLA-DPB1*04:01 allele is associated with non-obstructive azoospermia in Japanese patients.

Human genetics - 1 Dec 2013

Jinam Timothy A, Nakaoka Hirofumi, Hosomichi Kazuyoshi, Mitsunaga Shigeki, Okada Hiroyuki, Tanaka Atsushi, Tanaka Kenichi, Inoue Ituro

Abstract excerpt

Azoospermia is defined by absence of sperm in the semen and can either be caused by obstruction of the seminal tract (obstructive azoospermia) or by defects in spermatogenesis (non-obstructive azoospermia, NOA). Previous studies reported that specific alleles and single nucleotide polymorphisms (...

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Identifiers

PMID: 23934009
DOI: 10.1007/s00439-013-1347-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23934009-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

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Research trail→

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HLA-DPB1*04:01 allele is associated with non-obstructive azoospermia in Japanese patients.PMID 23934009Read ↗

Susceptibility gene for non-obstructive azoospermia located near HLA-DR and -DQ loci in the HLA class II region.Semantic proximity Read ↗

Association and meta-analysis of HLA and non-obstructive azoospermia in the Han Chinese population.Semantic proximity Read ↗

Susceptibility locus for non-obstructive azoospermia is localized within the HLA-DR/DQ subregion: primary role of DQB1*0604.Semantic proximity Read ↗

Genome-wide Loci linked to non-obstructive azoospermia susceptibility may be independent of reduced sperm production in males with normozoospermia.Semantic proximity Read ↗

HLA-DR antigen and HLA-DRB1 genotyping with nonobstructive azoospermia in Japan.Semantic proximity Read ↗

A genome-wide association study reveals that variants within the HLA region are associated with risk for nonobstructive azoospermia.Semantic proximity Read ↗

Genetic study of Hormad1 and Hormad2 with non-obstructive azoospermia patients in the male Chinese population.Semantic proximity Read ↗

Pathogenic variants screening in five non-obstructive azoospermia-associated genes.Semantic proximity Read ↗

A genome-wide association study in Chinese men identifies three risk loci for non-obstructive azoospermia.Semantic proximity Read ↗

Analysis of TATA-box binding protein associated factor 4b gene mutations in a Chinese population with nonobstructive azoospermia.Semantic proximity Read ↗

Replication study and meta-analysis of human nonobstructive azoospermia in Japanese populations.Semantic proximity Read ↗

Association of genetic variants in SOHLH1 and SOHLH2 with non-obstructive azoospermia risk in the Chinese population.Semantic proximity Read ↗

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