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Estimating the Lowest Detectable Dose of Ionizing Radiation by the Cytokinesis-Block Micronucleus Assay

9 Aug 2013

Abstract excerpt

The frequency of binucleated cells containing one or more micronuclei (MNBN cells) in cytokinesis-blocked peripheral blood lymphocytes can be used to determine whether a person has received an overexposure to ionizing radiation. However, the absence of a pre-exposure sample can preclude precise dosimetry. Here we use a database of MNBN cell frequencies in peripheral blood lymphocytes from 3,104 apparently...

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PMID: 23931722
DOI: 10.1667/rr3346.1

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