Article
The cytokinesis-block micronucleus technique: a detailed description of the method and its application to genotoxicity studies in human populations.
Mutation research - 1 Jan 1993
Fenech M
Abstract excerpt
The development of the cytokinesis-block (CB) technique has transformed the human-lymphocyte micronucleus assay (MN) into a reliable and precise method for assessing chromosome damage. Recent studies in our laboratory have confirmed that this method is a sensitive indicator of in vivo radiation exposure in (a) patients undergoing fractionated partial-body radiotherapy and (b) rodents exposed to uniform whole-body...
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