Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effects of external stimuli on the pacemaker function of the sinoatrial node in sodium channel gene mutations models.

Science China. Life sciences - 1 Sept 2013

Zhang Jiqian, Li Xiang, Liang Lisi, Huang Shoufang, Zhang Henggui

Abstract excerpt

Loss of function and gain of function mutations of the sodium channel were investigated using an intact two-dimensional rabbit sinoatrial node (SAN) and atrial cell model. The effects of three external stimuli (acetylcholine secretion by the vagal nerve, acid-base concentration, and tissue temper...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mutation
Share to Sodium Channels
Share to Vagus Nerve

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23929003
DOI: 10.1007/s11427-013-4533-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23929003-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Effects of external stimuli on the pacemaker function of the sinoatrial node in sodium channel gene mutations models.PMID 23929003Read ↗

[A simulation study for the effect of acid concentration and temperture on sick sinus syndrome].Semantic proximity Read ↗

Computational analysis of the human sinus node action potential: model development and effects of mutations.Semantic proximity Read ↗

Mechanistic links between Na+ channel (SCN5A) mutations and impaired cardiac pacemaking in sick sinus syndrome.Semantic proximity Read ↗

Isoprenaline: a potential contributor in sick sinus syndrome--insights from a mathematical model of the rabbit sinoatrial node.Semantic proximity Read ↗

A mathematical model of action potentials of mouse sinoatrial node cells with molecular bases.Semantic proximity Read ↗

Dynamics of PKA phosphorylation and gain of function in cardiac pacemaker cells: a computational model analysis.Semantic proximity Read ↗

A model of cellular cardiac-neural coupling that captures the sympathetic control of sinoatrial node excitability in normotensive and hypertensive rats.Semantic proximity Read ↗

Lack of potentiating effect of increasing temperature on responses to chemical activators in vagal sensory neurons isolated from TRPV1-null mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.