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Article

Optimal policies of non-cross-resistant chemotherapy on Goldie and Coldman's cancer model.

Mathematical biosciences - 1 Oct 2013

Chen Jeng-Huei, Kuo Ya-Hui, Luh Hsing Paul

Abstract excerpt

Mathematical models can be used to study the chemotherapy on tumor cells. Especially, in 1979, Goldie and Coldman proposed the first mathematical model to relate the drug sensitivity of tumors to their mutation rates. Many scientists have since referred to this pioneering work because of its simplicity and elegance. Its original idea has also been extended and further investigated in massive follow-up studies of...

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Identifiers

PMID: 23927854
DOI: 10.1016/j.mbs.2013.07.020

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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