Article
Arctigenin effectively ameliorates memory impairment in Alzheimer's disease model mice targeting both β-amyloid production and clearance.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 7 Aug 2013
Zhu Zhiyuan, Yan Jianming, Jiang Wei, Yao Xin-gang, Chen Jing, Chen Lili, Li Chenjing, Hu Lihong, Jiang Hualiang, Shen Xu
Abstract excerpt
Alzheimer's disease (AD) chiefly characterizes a progressively neurodegenerative disorder of the brain, and eventually leads to irreversible loss of intellectual abilities. The β-amyloid (Aβ)-induced neurodegeneration is believed to be the main pathological mechanism of AD, and Aβ production inhi...
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