Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Taking aim at Alzheimer's disease through the mammalian target of rapamycin

8 Aug 2014

Abstract excerpt

A significant portion of the world's population suffers from sporadic Alzheimer's disease (AD) with available present therapies limited to symptomatic care that does not alter disease progression. Over the next decade, advancing age of the global population will dramatically increase the incidence of AD and severely impact health care resources, necessitating novel, safe, and efficacious strategies for AD. The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Microtubule and mitosis dynamics
Share to PI3K/AKT/mTOR signaling in cancer
Share to Tuberous Sclerosis Complex Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25105207
DOI: 10.3109/07853890.2014.941921

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Taking aim at Alzheimer's disease through the mammalian target of rapamycinPMID 25105207Read ↗

Targeting molecules to medicine with mTOR, autophagy and neurodegenerative disordersSemantic proximity Read ↗

Mammalian/mechanistic target of rapamycin (mTOR) complexes in neurodegenerationSemantic proximity Read ↗

The mammalian target of rapamycin at the crossroad between cognitive aging and Alzheimer’s diseaseSemantic proximity Read ↗

mTOR signaling as a molecular target for the alleviation of Alzheimer's disease pathogenesisSemantic proximity Read ↗

Shedding new light on neurodegenerative diseases through the mammalian target of rapamycinSemantic proximity Read ↗

The mechanistic target of rapamycin (mTOR) and the silent mating-type information regulation 2 homolog 1 (SIRT1): oversight for neurodegenerative disordersSemantic proximity Read ↗

Targeting the core of neurodegeneration: FoxO, mTOR, and SIRT1Semantic proximity Read ↗

A Critical Kinase Cascade In Neurological Disorders: Pi3K, Akt and MtorSemantic proximity Read ↗

mTOR Mysteries: Nuances and Questions About the Mechanistic Target of Rapamycin in NeurodegenerationSemantic proximity Read ↗

Dysfunction of the mTOR pathway is a risk factor for Alzheimer’s diseaseSemantic proximity Read ↗

Dysregulated mTOR networks in experimental sporadic Alzheimer’s diseaseSemantic proximity Read ↗

The PI3K/Akt signaling axis in Alzheimer’s disease: a valuable target to stimulate or suppress?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.