Article
Repeat-associated non-ATG (RAN) translation in neurological disease.
Human molecular genetics - 15 Oct 2013
Cleary John D, Ranum Laura P W
Abstract excerpt
Well-established rules of translational initiation have been used as a cornerstone in molecular biology to understand gene expression and to frame fundamental questions on what proteins a cell synthesizes, how proteins work and to predict the consequences of mutations. For a group of neurological diseases caused by the abnormal expansion of short segments of DNA (e.g. CAG•CTG repeats), mutations within or outside...
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