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Article

Repeat-associated non-ATG (RAN) translation.

The Journal of biological chemistry - 19 Oct 2018

Cleary John Douglas, Pattamatta Amrutha, Ranum Laura P W

Abstract excerpt

Microsatellite expansions cause more than 40 neurological disorders, including Huntington's disease, myotonic dystrophy, and C9ORF72 amyotrophic lateral sclerosis/frontotemporal dementia (ALS/FTD). These repeat expansion mutations can produce repeat-associated non-ATG (RAN) proteins in all three reading frames, which accumulate in disease-relevant tissues. There has been considerable interest in RAN protein...

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Identifiers

PMID: 30213863
DOI: 10.1074/jbc.R118.003237
PMCID: PMC6200949

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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