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Article

Class II genes of miniature swine. IV. Characterization and expression of two allelic class II DQB cDNA clones.

Journal of immunology (Baltimore, Md. : 1950) - 15 Sept 1990

Gustafsson K, LeGuern C, Hirsch F, Germana S, Pratt K, Sachs D H

Abstract excerpt

Two cDNA clones coding for allelic miniature swine MHC class II Ag DQB chains have been isolated, characterized, and shown to be expressed after transfection into mouse fibroblasts. The two alleles differ at the nucleotide level by an overwhelming proportion of replacement substitutions, suggesting the influence of selection for polymorphism. Most of the resulting predicted amino acid replacements are in regions...

Topics

Alleles
Amino Acid Sequence
Animals
Base Sequence
Biological Evolution
Cloning, Molecular
DNA
Histocompatibility Antigens Class II
Major Histocompatibility Complex
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sequence Homology, Nucleic Acid

Swine

Swine, Miniature

Transfection

Source

Identifiers

PMID: 2391424

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2391424-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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