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Article

Diversification of porcine MHC class II genes: evidence for selective advantage.

Immunogenetics - 1 Feb 2009

Luetkemeier Erin S, Malhi Ripan S, Beever Jonathan E, Schook Lawrence B

Abstract excerpt

The major histocompatibility complex (MHC) is an immunological gene-dense region of high diversity in mammalian species. Sus scrofa was domesticated by at least six independent events over Eurasia during the Holocene period. It has been hypothesized that the level and distribution of MHC variation in pig populations reflect genetic selection and environmental influences. In an effort to define the complexity of...

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PMID: 19142631
DOI: 10.1007/s00251-008-0348-5

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