Article

Integrative Analysis of Dna Methylation and Gene Expression Profiles to Explore Potential Biomarkers of Glioblastoma

2021-03-06

Abstract excerpt

Glioblastoma multiform (GBM) is the most common, most invasive, and malignant type of primary brain tumor with poorly prognosis and poorly survival rate. Using GSE22891 the expression and methylation status of same GBM patients was evaluated to explore key epigenetic genes in GBM. Using |log2FC| > 1 and FDR < 0.05 as the threshold, DEGs including 4910 downregulated and 2478 upregulated were screened and by |log2FC...

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Literature Corpus work: fb65ca85-9855-56c0-bb76-7a14d51257f7
DOI: 10.21203/rs.3.rs-272827/v1

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