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Article

Resistin mediates the hepatic stellate cell phenotype.

World journal of gastroenterology - 28 Jul 2013

Dong Zhi-Xia, Su Lin, Brymora Joanne, Bird Claire, Xie Qing, George Jacob, Wang Jian-Hua

Abstract excerpt

AIM: To describe the role of resistin in liver fibrosis. METHODS: For the in vivo animal study, Sprague Dawley rats were subjected to bile duct ligation (BDL) for 4 wk. Rat liver, adipose tissue (epididymal fat) and serum were analyzed for resistin expression. For the in vitro experiment, rat primary hepatic stellate cells (HSCs) and Kupffer cells (KCs) were used. HSCs were exposed to recombinant resistin, and...

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Identifiers

PMID: 23901222
DOI: 10.3748/wjg.v19.i28.4475
PMCID: PMC3725371

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