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Article

Adaptive strategies and pathogenesis of Clostridium difficile from in vivo transcriptomics.

Infection and immunity - 1 Oct 2013

Janoir Claire, Denève Cécile, Bouttier Sylvie, Barbut Frédéric, Hoys Sandra, Caleechum Laxmee, Chapetón-Montes Diana, Pereira Fátima C, Henriques Adriano O, Collignon Anne, Monot Marc, Dupuy Bruno

Abstract excerpt

Clostridium difficile is currently the major cause of nosocomial intestinal diseases associated with antibiotic therapy in adults. In order to improve our knowledge of C. difficile-host interactions, we analyzed the genome-wide temporal expression of C. difficile 630 genes during the first 38 h of mouse colonization to identify genes whose expression is modulated in vivo, suggesting that they may play a role in...

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Identifiers

PMID: 23897605
DOI: 10.1128/IAI.00515-13
PMCID: PMC3811758

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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