Article
Variants in phospholipid metabolism and upstream regulators and non-small cell lung cancer susceptibility.
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico - 1 Jan 2014
Cebrián A, Taron M, Sala N, Ardanaz E, Chirlaque M-D, Larrañaga N, Redondo M-L, Sánchez M-J, Gómez del Pulgar T, Camps C, Rosell R, González C A, Lacal J C
Abstract excerpt
AIM: The relevance of the cytidine diphosphate-choline and Rho GTPases pathways in the pathogenesis of cancer has been previously demonstrated. We investigate by a case-control association study if genetics variants in these pathways are associated with risk of developing lung cancer. METHODS: Thirty-seven tag SNPs were evaluated as risk factor of NSCLC in 897 cases and 904 controls. RESULTS: Six SNPs were...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.