Article
8-Oxoguanine DNA glycosylase 1 (ogg1) maintains the function of cardiac progenitor cells during heart formation in zebrafish.
Experimental cell research - 15 Nov 2013
Yan Lifeng, Zhou Yong, Yu Shanhe, Ji Guixiang, Wang Lei, Liu Wei, Gu Aihua
Abstract excerpt
Genomic damage may devastate the potential of progenitor cells and consequently impair early organogenesis. We found that ogg1, a key enzyme initiating the base-excision repair, was enriched in the embryonic heart in zebrafish. So far, little is known about DNA repair in cardiogenesis. Here, we a...
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