Article
Infectivity of a genotype 4 hepatitis E virus cDNA clone by intrahepatic inoculation of laboratory rats.
Veterinary microbiology - 25 Oct 2013
Zhu Yumin, Yu Xiaoming, Zhang Yuanshu, Ni Yanyan, Si Fusheng, Yu Ruisong, Dong Shijuan, Huang Yaowei, Li Zhen
Abstract excerpt
A cDNA clone of a genotype 4 swine hepatitis E virus (HEV) strain (SAAS-FX17), identified in Shanghai, has been constructed. Capped RNA transcripts were prepared in vitro and shown to be replication-competent in Huh7 cells. Sprague-Dawley (SD) rats administered the RNA transcripts by intrahepatic...
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