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Construction and characterization of infectious cDNA clones of a chicken strain of hepatitis E virus (HEV), avian HEV

12 Aug 2005

Abstract excerpt

Hepatitis E virus (HEV), the causative agent of hepatitis E, is an important human pathogen. Increasing evidence indicates that hepatitis E is a zoonosis. Avian HEV was recently discovered in chickens with hepatitis-splenomegaly syndrome in the USA. Like swine HEV from pigs, avian HEV is also genetically and antigenically related to human HEV. The objective of this study was to construct and characterize an...

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PMID: 16099918
DOI: 10.1099/vir.0.81070-0

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