Article
Cell Culture of a Swine Genotype 4 Hepatitis E Virus Strain.
Journal of medical virology - 1 Nov 2024
Gong Ga, Xin Jiaojiao, Lou Yongzhi, Qiong Da, Dawa Zhuoma, Gesang Zhuoma, Suolang Sizhu
Abstract excerpt
HEV infection has become a global health concern. The study of HEV pathogenicity has been hindered by the lack of a suitable in vitro culture system. In the present research, we systematic demonstration of efficient replication of swine GT4 HEV in A549 cells, Huh-7 cells, and HepG2/C3A cell lines. The results of the immunofluorescence assay and immunofluorescence confocal assay showed that swine GT4 HEV is...
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