Article
Evidence for epigenetic alterations in Turner syndrome opens up feasibility of new pharmaceutical interventions.
Current pharmaceutical design - 1 Jan 2014
Rajpathak Shriram N, Deobagkar Deepti D
Abstract excerpt
DNA methylation is an important regulatory component which influences phenotypes by modulating gene expression. Changes in DNA methylation may lead to altered phenotypes and ability of an organism to respond to stress leading to subsequent manifestation of life style diseases, cancer, etc. The human X chromosome represents a classical model for epigenetic processes governing differential regulation of homologous...
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