Article
Mutations in the reverse transcriptase and protease genes of human immunodeficiency virus-1 from antiretroviral naïve and treated pediatric patients.
Viruses - 10 Feb 2015
Bure Dinesh, Makhdoomi Muzamil A, Lodha Rakesh, Prakash Somi Sankaran, Kumar Rajesh, Parray Hilal A, Singh Ravinder, Kabra Sushil K, Luthra Kalpana
Abstract excerpt
The success of highly active antiretroviral therapy (HAART) is challenged by the emergence of resistance-associated mutations in human immunodeficiency virus-1 (HIV-1). In this study, resistance associated mutations in the reverse transcriptase (RT) and protease (PR) genes in antiretroviral therapy (ART) naïve and treated HIV-1 infected pediatric patients from North India were evaluated. Genotyping was...
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