Article
A genome-wide association study of atopic dermatitis identifies loci with overlapping effects on asthma and psoriasis.
Human molecular genetics - 1 Dec 2013
Weidinger Stephan, Willis-Owen Saffron A G, Kamatani Yoichiro, Baurecht Hansjörg, Morar Nilesh, Liang Liming, Edser Pauline, Street Teresa, Rodriguez Elke, O'Regan Grainne M, Beattie Paula, Fölster-Holst Regina, Franke Andre, Novak Natalija, Fahy Caoimhe M, Winge Mårten C G, Kabesch Michael, Illig Thomas, Heath Simon, Söderhäll Cilla, Melén Erik, Pershagen Göran, Kere Juha, Bradley Maria, Lieden Agne, Nordenskjold Magnus, Harper John I, McLean W H Irwin, Brown Sara J, Cookson William O C, Lathrop G Mark, Irvine Alan D, Moffatt Miriam F
Abstract excerpt
Atopic dermatitis (AD) is the most common dermatological disease of childhood. Many children with AD have asthma and AD shares regions of genetic linkage with psoriasis, another chronic inflammatory skin disease. We present here a genome-wide association study (GWAS) of childhood-onset AD in 1563 European cases with known asthma status and 4054 European controls. Using Illumina genotyping followed by imputation,...
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