Article
Genetic variations and polymorphisms in the ezrin gene are associated with age-related cataract.
Molecular vision - 1 Jan 2013
Lin Qinghong, Zhou Nan, Zhang Na, Zhu Bidan, Hu Shanshan, Zhou Zhou, Qi Yanhua
Abstract excerpt
PURPOSE: Age-related cataract (ARC) is a complex multifactorial disorder, including genetic and environmental factors. Ezrin (EZR), a member of the ezrin/radixin/moesin (ERM) protein family, plays a crucial role in the development of the lens as a plasma membrane-cytoskeleton linker. We conducted this study to investigate the role of genetic variations of ezrin and the relationship between single nucleotide...
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