Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutational screening of EFNA5 in Chinese age-related cataract patients.

Ophthalmic research - 1 Jan 2014

Lin Qinghong, Zhou Nan, Zhang Na, Qi Yanhua

Abstract excerpt

BACKGROUND/AIM: In the past few years, Ephrin-A5 (EFNA5) had been identified to be associated with lens development, but so far no sequence variation in EFNA5 has been reported in humans. Therefore, we conduct this study to investigate the EFNA5 genetic variations in Chinese age-related cataract (ARC) patients. METHODS: Sequencing of EFNA5 was performed in 140 sporadic ARC patients and 142 random unrelated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Asian People
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cataract

Share to DNA Mutational Analysis

Share to DNA Primers

Share to Gene Frequency

Source

Identifiers

PMID: 25300504
DOI: 10.1159/000363139

Genes

EFNA5
ARC

Variants

rs201008479

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutational screening of EFNA5 in Chinese age-related cataract patients.PMID 25300504Read ↗

Functional analysis of deleterious EPHA2 SNPs in lens epithelial cells.Semantic proximity Read ↗

Functional analysis of deleterious EPHA2 SNPs in lens epithelial cells.Semantic proximity Read ↗

A novel splice donor site mutation in EPHA2 caused congenital cataract in a Chinese family.Semantic proximity Read ↗

Association of EPHA2 polymorphisms and age-related cortical cataract in a Han Chinese population.Semantic proximity Read ↗

Novel mutations identified in Chinese families with autosomal dominant congenital cataracts by targeted next-generation sequencing.Semantic proximity Read ↗

Mutations in the EPHA2 gene are a major contributor to inherited cataracts in South-Eastern Australia.Semantic proximity Read ↗

Exome sequencing identifies a novel mutation in GJA8 associated with inherited cataract in a Chinese family.Semantic proximity Read ↗

EPHA2 Polymorphisms in Estonian Patients with Age-Related Cataract.Semantic proximity Read ↗

The EPHA2 gene is associated with cataracts linked to chromosome 1p.Semantic proximity Read ↗

Germ-line and somatic EPHA2 coding variants in lens aging and cataract.Semantic proximity Read ↗

Genetic variations in GJA3, GJA8, LIM2, and age-related cataract in the Chinese population: a mutation screening study.Semantic proximity Read ↗

Single nucleotide polymorphism (rs7543472) in EPHA2 gene is associated with age-related cataract in subjects enrolled from Multan in southern Punjab: A case-control study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.