Article
The Influence of Endothelial Nitric Oxide Synthase (eNOS) Genetic Polymorphisms on Cholesterol Blood Levels Among Type 2 Diabetic Patients on Atorvastatin Therapy.
Endocrine, metabolic & immune disorders drug targets - 1 Jan 2021
Abdullah Sarah, Jarrar Yazun, Alhawari Hussam, Abed Eyada, Zihlif Malek
Abstract excerpt
BACKGROUND: Endothelial nitric oxide synthase (eNOS) plays a major role in the response of anti-hypercholesterol statin drugs. Genetic polymorphisms in the eNOS gene affect the activity of eNOS thereby modulating the statin response. OBJECTIVE: This study investigated the influence of major functional eNOS gene polymorphisms (rs2070744, rs1799983, and rs61722009) on the lipid profile of type 2 diabetes mellitus...
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