Article
Evaluation of genetic susceptibility loci for obesity in Chinese women.
American journal of epidemiology - 1 Aug 2010
Shi Jiajun, Long Jirong, Gao Yu-Tang, Lu Wei, Cai Qiuyin, Wen Wanqing, Zheng Ying, Yu Kai, Xiang Yong-Bing, Hu Frank B, Zheng Wei, Shu Xiao-Ou
Abstract excerpt
Recent genome-wide association (GWA) studies have identified 18 genetic loci for obesity. Using directly observed and imputed GWA genotyping data on approximately 5,000 Chinese women (1996-2007), the authors evaluated 17 single nucleotide polymorphisms (SNPs) that represent 17 distinct obesity loci. Two SNPs near the BAT2 and MC4R genes and 3 SNPs within the FTO, SEC16B, and SH2B1 genes were significantly...
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