Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A genetic variant in long non-coding RNA HULC contributes to risk of HBV-related hepatocellular carcinoma in a Chinese population.

PloS one - 1 Jan 2012

Liu Yao, Pan Shandong, Liu Li, Zhai Xiangjun, Liu Jibin, Wen Juan, Zhang Yixin, Chen Jianguo, Shen Hongbing, Hu Zhibin

Abstract excerpt

BACKGROUND: Recently, several studies have demonstrated that two long non-coding RNAs (lncRNAs), HULC and MALAT1, may participate in hepatocellular carcinoma (HCC) development and progression. However, genetic variations in the two lncRNAs and their associations with HCC susceptibility have not been reported. In this study, we hypothesized that single nucleotide polymorphisms (SNPs) in HULC and MALAT1 may...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asian People
Share to Carcinoma, Hepatocellular

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to Genetic Predisposition to Disease

Share to Hepatitis B virus

Share to Liver Neoplasms

Share to Polymorphism, Single Nucleotide

Share to Sequence Analysis, DNA

Source

Open in PubMed Open full text

Identifiers

PMID: 22493738
DOI: 10.1371/journal.pone.0035145
PMCID: PMC3320879

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A genetic variant in long non-coding RNA HULC contributes to risk of HBV-related hepatocellular carcinoma in a Chinese population.PMID 22493738Read ↗

The expression of long non coding RNA genes is associated with expression with polymorphisms of HULC rs7763881 and MALAT1 rs619586 in hepatocellular carcinoma and HBV Egyptian patientsSemantic proximity Read ↗

The association of lncRNA-HULC polymorphisms with hepatocellular cancer risk and prognosis.Semantic proximity Read ↗

The association of lncRNA SNPs and SNPs-environment interactions based on GWAS with HBV-related HCC risk and progression.Semantic proximity Read ↗

Associations between lncRNA-related polymorphisms and hepatocellular carcinoma risk: A two-stage case-control study.Semantic proximity Read ↗

Genetic polymorphisms in the miR-372 (rs12983273) and LncRNA HULC (rs7763881) genes and susceptibility to Hepatitis B virus (HBV) infection.Semantic proximity Read ↗

Involvement of long non-coding RNA HULC (highly up-regulated in liver cancer) in pathogenesis and implications for therapeutic interventionSemantic proximity Read ↗

Current State and Progress of Research on the Role of lncRNA in HBV-Related Liver CancerSemantic proximity Read ↗

miR-372 (rs12983273) and LncRNA HULC (rs7763881) Genetic Polymorphisms and Susceptibility to Hepatitis B Virus (HBV) InfectionSemantic proximity Read ↗

Long Noncoding RNA HULC Promoter Polymorphism rs1041279 Is Associated with an Increased Risk of Cervical Squamous Cell Carcinoma.Semantic proximity Read ↗

Association of twelve polymorphisms in three onco-lncRNA genes with hepatocellular cancer risk and prognosis: A case-control study.Semantic proximity Read ↗

Impact of NOTCH1 polymorphisms on liver cancer in a Chinese Han population.Semantic proximity Read ↗

Association of MBOAT7-TMC4 rs641738 with the risk of hepatocellular carcinoma and persistent infection of hepatitis B virus: a case-control study and meta-analysisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.