Article
A genetic variant in long non-coding RNA HULC contributes to risk of HBV-related hepatocellular carcinoma in a Chinese population.
PloS one - 1 Jan 2012
Liu Yao, Pan Shandong, Liu Li, Zhai Xiangjun, Liu Jibin, Wen Juan, Zhang Yixin, Chen Jianguo, Shen Hongbing, Hu Zhibin
Abstract excerpt
BACKGROUND: Recently, several studies have demonstrated that two long non-coding RNAs (lncRNAs), HULC and MALAT1, may participate in hepatocellular carcinoma (HCC) development and progression. However, genetic variations in the two lncRNAs and their associations with HCC susceptibility have not b...
Topics
- Asian People
- Carcinoma, Hepatocellular
- Carrier State
- Case-Control Studies
- Female
- Genetic Predisposition to Disease
- Hepatitis B virus
- Hepatitis B, Chronic
- Humans
- Liver Neoplasms
- Male
- Polymorphism, Single Nucleotide
- RNA, Long Noncoding
- RNA, Untranslated