Article
Breath tests to phenotype drug disposition in oncology.
Clinical pharmacokinetics - 1 Nov 2013
Opdam Frans L, Modak Anil S, Gelderblom Hans, Guchelaar Henk-Jan
Abstract excerpt
Breath tests (BTs) have been investigated as diagnostic tools to phenotype drug disposition in cancer patients in the pursuit to individualize drug treatment. The choice of the right phenotype probe is crucial and depends on the metabolic pathway of the anticancer agent of interest. BTs using orally or intravenously administered selective non-radioactive (13)C-labeled probes to non-invasively evaluate...
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