Article
ADAM33 gene polymorphisms and mortality. A prospective cohort study.
PloS one - 1 Jan 2013
Figarska Sylwia M, Vonk Judith M, van Diemen Cleo C, Postma Dirkje S, Boezen H Marike
Abstract excerpt
The ADAM33 gene is associated with the pathophysiology of Chronic Obstructive Pulmonary Disease (COPD) and atherosclerosis. In this study we investigated all-cause, COPD and cardiovascular mortality, in relation to single nucleotide polymorphisms (SNPs) in ADAM33 (Q_1, S_1, S_2, T_1 and T_2) that were genotyped in 1,390 subjects from the Vlagtwedde/Vlaardingen cohort. Participants were examined at entry in...
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