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Article

Genetic variants in ADAM33 are associated with airway inflammation and lung function in COPD.

BMC pulmonary medicine - 4 Nov 2014

Wang Xinyan, Li Wan, Huang Kun, Kang Xiaowen, Li Zhaoguo, Yang Chengcheng, Wu Xiaomei, Chen Lina

Abstract excerpt

BACKGROUND: Genetic factors play a role in the development and severity of chronic obstructive pulmonary disease (COPD). The pathogenesis of COPD is a multifactorial process including an inflammatory cell profile. Recent studies revealed that single nucleotide polymorphisms (SNPs) within ADAM33 increased the susceptibility to COPD through changing the airway inflammatory process and lung function. METHODS: In...

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Identifiers

PMID: 25369941
DOI: 10.1186/1471-2466-14-173
PMCID: PMC4228268

Genes

ADAM33

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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