Article
ADAM33 gene polymorphisms are associated with the risk of idiopathic pulmonary fibrosis.
Lung - 1 Aug 2014
Uh Soo-Taek, Jang An-Soo, Park Sung-Woo, Park Jong-Sook, Min Chang-Gi, Kim Yong Hoon, Park Byung-Lae, Shin Hyoung Doo, Kim Dong Soon, Park Choon-Sik
Abstract excerpt
BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is characterized by progressive dyspnea and worsening lung function due to remodeling of the lung, including epithelial mesenchymal transition. ADAM33 is a disintegrin and metalloprotease domain-containing protein, which may be related to lung fibrosis by exerting angiogenesis and remodeling of the lung. Thus, we evaluated the association of single-nucleotide...
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