Article
A disintegrin and metalloprotease 33 and chronic obstructive pulmonary disease pathophysiology.
Thorax - 1 Mar 2007
Gosman Margot M E, Boezen H Marike, van Diemen Cleo C, Snoeck-Stroband Jiska B, Lapperre Thérèse S, Hiemstra Pieter S, Ten Hacken Nick H T, Stolk Jan, Postma Dirkje S
Abstract excerpt
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a respiratory disorder with increasing prevalence and mortality. It is associated with airway obstruction, increased airway hyper-responsiveness (AHR), and ongoing airway and lung inflammation dominated by CD8 lymphocytes and neutrophils...
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