Article
Adam33 polymorphisms are associated with COPD and lung function in long-term tobacco smokers.
Respiratory research - 12 Mar 2009
Sadeghnejad Alireza, Ohar Jill A, Zheng Siqun L, Sterling David A, Hawkins Gregory A, Meyers Deborah A, Bleecker Eugene R
Abstract excerpt
BACKGROUND: Variation in ADAM33 has been shown to be important in the development of asthma and altered lung function. This relationship however, has not been investigated in the population susceptible to COPD; long term tobacco smokers. We evaluated the association between polymorphisms in ADAM33 gene with COPD and lung function in long term tobacco smokers. METHODS: Caucasian subjects, at least 50 year old, who...
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