Article
Genotype, phenotype, and karyotype correlation in the XO mouse model of Turner Syndrome.
The Journal of heredity - 1 Jan 2000
Probst Frank J, Cooper Mitchell Lance, Cheung Sau Wai, Justice Monica J
Abstract excerpt
The murine model for Turner Syndrome is the XO mouse. Unlike their human counterparts, XO mice are typically fertile, and their lack of a second sex chromosome can be transmitted from one generation to the next as an X-linked dominant trait with male lethality. The introduction of an X-linked coat-color marker (tabby) has greatly facilitated the maintenance of this useful mouse strain. XO mice can be produced in...
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