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Article

Pharmacodynamic genetic variants related to antipsychotic adverse reactions in healthy volunteers.

Pharmacogenomics - 1 Jul 2013

López-Rodríguez Rosario, Cabaleiro Teresa, Ochoa Dolores, Román Manuel, Borobia Alberto M, Carcas Antonio J, Ayuso Carmen, Novalbos Jesús, Abad-Santos Francisco

Abstract excerpt

AIM: Clinical trials with healthy volunteers are a useful model for evaluating safety and tolerability, without the interference of concomitant diseases and drugs. The present study aims to improve our understanding of antipsychotic-related adverse reactions (ARs) and their possible association with common genetic variants of pharmacodynamic proteins such as neurotransmitter receptors/transporters. MATERIALS &...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Drug-Related Side Effects and Adverse Reactions

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Source

Identifiers

PMID: 23859574
DOI: 10.2217/pgs.13.106

Genes

DRD2
COMT
DRD3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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