Article
Survivin gene promoter polymorphism -31G/C as a risk factor for keratocystic odontogenic tumor development.
European journal of oral sciences - 1 Feb 2012
Andric Miroslav, Nikolic Nađa, Boskovic Marija, Milicic Biljana, Skodric Sanja, Basta Jovanovic Gordana, Milasin Jelena
Abstract excerpt
Several single nucleotide polymorphisms in survivin gene promoters, notably -31G/C, have been shown to modulate the expression and activity of the survivin protein. Consequently, the -31G/C polymorphism has been identified as a risk factor for the development of several types of tumors. The aim of this study was to investigate a possible association between the -31G/C polymorphism and the risk for keratocystic...
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