Article
Functional polymorphisms in promoter survivin gene and its association with susceptibility to bladder cancer in North Indian cohort.
Molecular biology reports - 1 May 2012
Jaiswal Praveen Kumar, Goel Apul, Mandhani Anil, Mittal Rama Devi
Abstract excerpt
Survivin is a member of novel inhibitor of apoptosis protein family which expressed in human cancers. The molecular detection of bladder cancer by targeting Survivin as a novel marker may be useful in the occurrence and progression of cancer. We genotyped Survivin -31G>C, -1547A>G and -241C>T by PCR-restriction fragment length polymorphism to evaluate the risk of bladder cancer (BC) in 200 BC patients and 200...
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