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Article

Genome-wide DNA methylation patterns in discordant sib pairs with alcohol dependence.

Asia-Pacific psychiatry : official journal of the Pacific Rim College of Psychiatrists - 1 Mar 2013

Zhao Rongrong, Zhang Ruiling, Li Wenqiang, Liao Yanhui, Tang Jinsong, Miao Qin, Hao Wei

Abstract excerpt

INTRODUCTION: Alcohol dependence is a complex disease caused by a confluence of environmental and genetic factors. Epigenetic mechanisms have been shown to play an important role in the pathogenesis of alcohol dependence. METHODS: To determine if alterations in gene-specific methylation were associated with alcohol dependence, a genome-wide DNA methylation analysis was performed on peripheral blood mononuclear...

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Identifiers

PMID: 23857790
DOI: 10.1111/appy.12010

Genes

GABRP
DBH
GAD1
SSTR4

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