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Article

Genetic evidence linking retinol to birth weight: A two-sample Mendelian randomization study.

Reproductive toxicology (Elmsford, N.Y.) - 1 Dec 2024

Mu Fangxiang, Wang Kexin, Jiang Lu, Wang Fang

Abstract excerpt

This study aims to clarify the potential causal effects of dietary antioxidant vitamins on pregnancy outcomes (miscarriage, preterm labor, and birth weight) using Mendelian randomization (MR). Our instrumental variables (IVs) were single-nucleotide polymorphisms (SNPs) linked to retinol, vitamin C, carotene, and vitamin E (P < 5×10-6). The summary statistics for miscarriage, preterm labor, and birth weight were...

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Identifiers

PMID: 39477190
DOI: 10.1016/j.reprotox.2024.108739

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