Article
MALDI imaging on large-scale tissue microarrays identifies molecular features associated with tumour phenotype in oesophageal cancer.
Histopathology - 1 Oct 2013
Quaas Alexander, Bahar Ahmad Soliaman, von Loga Katharina, Seddiqi Ahmad Shoaib, Singer Julius Magnus, Omidi Maryam, Kraus Olga, Kwiatkowski Marcel, Trusch Maria, Minner Sarah, Burandt Eike, Stahl Phillip, Wilczak Waldemar, Wurlitzer Marcus, Simon Ronald, Sauter Guido, Marx Andreas, Schlüter Hartmut
Abstract excerpt
AIMS: Matrix-assisted laser desorption/ionisation mass spectrometry imaging (MALDI-MSI) and tissue microarray (TMA) technologies were jointly utilized to search for molecular features associated with clinicopathological parameters in oesophageal cancer. METHODS AND RESULTS: Two TMAs from formalin-fixed tissue samples, including 300 adenocarcinomas and 177 squamous cell carcinomas with clinical follow-up data,...
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