Article
Delineation of disease phenotypes associated with esophageal adenocarcinoma by MALDI-IMS-MS analysis of serum N-linked glycans.
The Analyst - 2 May 2017
Gaye M M, Ding T, Shion H, Hussein A, Hu Y, Zhou S, Hammoud Z T, Lavine B K, Mechref Y, Gebler J C, Clemmer D E
Abstract excerpt
N-Linked glycans, extracted from patient sera and healthy control individuals, are analyzed by Matrix-assisted laser desorption ionization (MALDI) in combination with ion mobility spectrometry (IMS), mass spectrometry (MS) and pattern recognition methods. MALDI-IMS-MS data were collected in duplicate for 58 serum samples obtained from individuals diagnosed with Barrett's esophagus (BE, 14 patients), high-grade...
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