Article
MALDI profiles of proteins and lipids for the rapid characterisation of upper GI-tract cancers.
Journal of proteomics - 27 Mar 2013
Singhal Rishi, Carrigan John B, Wei Wenbin, Taniere Phillipe, Hejmadi Rahul K, Forde Colm, Ludwig Christian, Bunch Josephine, Griffiths Rian L, Johnson Philip J, Tucker Olga, Alderson Derek, Günther Ulrich L, Ward Douglas G
Abstract excerpt
AIM: To identify a reliable MALDI 'cancer fingerprint' to aid in the rapid detection and characterisation of malignant upper GI-tract disease from endoscopic biopsies. METHODS: A total of 183 tissue biopsies were collected from 126 patients with or without oesophago-gastric malignancy and proteins and lipids separated by methanol/chloroform extraction. Peak intensities in the lipid and protein MALDI spectra from...
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