Article
Analysis of colorectal adenocarcinoma tissue by desorption electrospray ionization mass spectrometric imaging.
Analytical and bioanalytical chemistry - 1 Jun 2012
Gerbig Stefanie, Golf Ottmar, Balog Julia, Denes Julia, Baranyai Zsolt, Zarand Attila, Raso Erzsebet, Timar Jozsef, Takats Zoltan
Abstract excerpt
Negative ion desorption electrospray ionization (DESI) was used for the analysis of an ex vivo tissue sample set comprising primary colorectal adenocarcinoma samples and colorectal adenocarcinoma liver metastasis samples. Frozen sections (12 μm thick) were analyzed by means of DESI imaging mass spectrometry (IMS) with spatial resolution of 100 μm using a computer-controlled DESI imaging stage mounted on a high...
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