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Article

Interplay between siderophores and colibactin genotoxin biosynthetic pathways in Escherichia coli.

PLoS pathogens - 1 Jan 2013

Martin Patricia, Marcq Ingrid, Magistro Giuseppe, Penary Marie, Garcie Christophe, Payros Delphine, Boury Michèle, Olier Maïwenn, Nougayrède Jean-Philippe, Audebert Marc, Chalut Christian, Schubert Sören, Oswald Eric

Abstract excerpt

In Escherichia coli, the biosynthetic pathways of several small iron-scavenging molecules known as siderophores (enterobactin, salmochelins and yersiniabactin) and of a genotoxin (colibactin) are known to require a 4'-phosphopantetheinyl transferase (PPTase). Only two PPTases have been clearly identified: EntD and ClbA. The gene coding for EntD is part of the core genome of E. coli, whereas ClbA is encoded on the...

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PMID: 23853582
DOI: 10.1371/journal.ppat.1003437
PMCID: PMC3708854

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Source receipt: pubmed, retrieved 7 Sept 2026.

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