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Article

The effector repertoire of enteropathogenic E. coli: ganging up on the host cell

13 Jan 2009

Abstract excerpt

Diarrhoeal disease caused by enteropathogenic E. coli (EPEC) is dependent on a delivery system that injects numerous bacterial 'effector' proteins directly into host cells. The best-described EPEC effectors are encoded together on the locus of enterocyte effacement (LEE) pathogenicity island and display high levels of multifunctionality and cooperativity within the host cell. More recently, effectors encoded...

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PMID: 19144561
DOI: 10.1016/j.mib.2008.11.006

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