Article
Correlation between relatives given complete genotypes: from identity by descent to identity by function.
Theoretical population biology - 1 Sept 2013
Sverdlov Serge, Thompson Elizabeth A
Abstract excerpt
In classical quantitative genetics, the correlation between the phenotypes of individuals with unknown genotypes and a known pedigree relationship is expressed in terms of probabilities of IBD states. In existing approaches to the inverse problem where genotypes are observed but pedigree relationships are not, dependence between phenotypes is either modeled as Bayesian uncertainty or mapped to an IBD model via...
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