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Article

DLin-7 is required in postsynaptic lamina neurons to prevent light-induced photoreceptor degeneration in Drosophila.

Current biology : CB - 22 Jul 2013

Soukup Sandra-Fausia, Pocha Shirin Meher, Yuan Michaela, Knust Elisabeth

Abstract excerpt

Inherited retinal degeneration in humans is caused by mutations in a wide spectrum of genes that regulate photoreceptor development and homeostasis. Many of these genes are structurally and functionally conserved in Drosophila, making the fly eye an ideal system in which to study the cellular and molecular basis of blindness. DLin-7, the ortholog of vertebrate MALS/Veli, is a core component of the evolutionarily...

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Share to Adaptor Proteins, Signal Transducing
Share to Cell Adhesion Molecules

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunoprecipitation

Share to Microscopy, Electron, Transmission

Share to Photoreceptor Cells, Invertebrate

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Source

Identifiers

PMID: 23850283
DOI: 10.1016/j.cub.2013.05.060

Genes

CASK
CRB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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