HLA specificities are related to development and prognosis of diffuse large B-cell lymphoma.

doi:10.1182/blood-2013-02-483420

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Article

HLA specificities are related to development and prognosis of diffuse large B-cell lymphoma.

Blood - 22 Aug 2013

Alcoceba Miguel, Sebastián Elena, Marín Luis, Balanzategui Ana, Sarasquete M Eugenia, Chillón M Carmen, Jiménez Cristina, Puig Noemí, Corral Rocío, Pardal Emilia, Grande Carlos, Bello José Luis, Albo Carmen, de la Cruz Fátima, Panizo Carlos, Martín Alejandro, González-Barca Eva, Caballero M Dolores, San Miguel Jesús F, García-Sanz Ramón, González Marcos

Abstract excerpt

Diffuse large B-cell lymphoma (DLBCL) is an aggressive disease influenced by genetic and environmental factors. The role of the HLA system in tumor antigen presentation could be involved in susceptibility and disease control. We analyzed the phenotypic frequencies of HLA-A, HLA-B, HLA-C, HLA-DRB1, and HLA-DQB1 in 250 DLBCLs, comparing them with 1940 healthy individuals. We also evaluated the influence of HLA...

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PMID: 23843497
DOI: 10.1182/blood-2013-02-483420

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