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Article

Further investigation of the role of HLA-DPB1 in adult Hodgkin's disease (HD) suggests an influence on susceptibility to different HD subtypes.

British journal of cancer - 1 Jul 1999

Taylor G M, Gokhale D A, Crowther D, Woll P J, Harris M, Ryder D, Ayres M, Radford J A

Abstract excerpt

It has been suggested in a number of studies that susceptibility to adult Hodgkin's disease (HD) is influenced by the HLA class II region, and specifically by alleles at the HLA-DPB1 locus. Since HD is diagnostically complex, it is not clear whether different HLA-DPB1 alleles confer susceptibility to different HD subtypes. To clarify this we have extended a previous study to type DPB1 alleles in 147 adult HD...

Topics

Adolescent
Adult
Alleles
Disease Susceptibility
Female
HLA-DP Antigens
HLA-DP beta-Chains
Hodgkin Disease
Humans
Male
Middle Aged

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Identifiers

PMID: 10424743
DOI: 10.1038/sj.bjc.6690536
PMCID: PMC2363076

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