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Igf Signaling is Required for Cardiomyocyte Proliferation during Zebrafish Heart Development and Regeneration

26 Jun 2013

Abstract excerpt

Unlike its mammalian counterpart, the adult zebrafish heart is able to fully regenerate after severe injury. One of the most important events during the regeneration process is cardiomyocyte proliferation, which results in the replacement of lost myocardium. Growth factors that induce cardiomyocyte proliferation during zebrafish heart regeneration remain to be identified. Signaling pathways important for heart...

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PMID: 23840646
DOI: 10.1371/journal.pone.0067266

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